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Distribution and temporal variability of the solar resource at a site in south-east Norway

Muyiwa S. ADARAMOLA

Frontiers in Energy 2016, Volume 10, Issue 4,   Pages 375-381 doi: 10.1007/s11708-016-0426-6

Abstract: that the inter-annual coefficient of variation of the global solar radiation is 4.28%, while that of diffuse

Keywords： coefficient of variation     global solar radiation     diffuse ratio     albedo     PV energy systems    

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Fully integrated approach: an alternative solution of coupling a GIS and diffuse pollution models

S. LIU,R.E. BRAZIER,A. L. HEATHWAITE,W. LIU

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 4,   Pages 616-623 doi: 10.1007/s11783-013-0589-x

Abstract: analysis of spatially referred information, GIS has been recognized as a method to aid the modeling of diffuseA common question in integrating diffuse pollution models and GIS is to choose a suitable coupling approach, in which the feature of diffuse pollution models should be taken into account.In this paper, we report on our experience in coupling a distributed diffuse pollution model with a GISexecution and more robust than loose and tight coupling approaches and is suitable for distributed diffuse

Keywords： diffuse pollution     GIS     modeling     nutrients     phosphorus    

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Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 240-262 doi: 10.1007/s11684-022-0936-z

Abstract: Detailed characterizations of genomic alterations have not identified subtype-specific vulnerabilities in adult gliomas. Mapping gliomas into developmental programs may uncover new vulnerabilities that are not strictly related to genomic alterations. After identifying conserved gene modules co-expressed with EGFR or PDGFRA (EM or PM), we recently proposed an EM/PM classification scheme for adult gliomas in a histological subtype- and grade-independent manner. By using cohorts of bulk samples, paired primary and recurrent samples, multi-region samples from the same glioma, single-cell RNA-seq samples, and clinical samples, we here demonstrate the temporal and spatial stability of the EM and PM subtypes. The EM and PM subtypes, which progress in a subtype-specific mode, are robustly maintained in paired longitudinal samples. Elevated activities of cell proliferation, genomic instability and microenvironment, rather than subtype switching, mark recurrent gliomas. Within individual gliomas, the EM/PM subtype was preserved across regions and single cells. Malignant cells in the EM and PM gliomas were correlated to neural stem cell and oligodendrocyte progenitor cell compartment, respectively. Thus, while genetic makeup may change during progression and/or within different tumor areas, adult gliomas evolve within a neurodevelopmental framework of the EM and PM molecular subtypes. The dysregulated developmental pathways embedded in these molecular subtypes may contain subtype-specific vulnerabilities.

Keywords： glioma progression     molecular classification     EM/PM subtyping     intratumor heterogeneity    

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Immunosuppressive tumor microenvironment contributes to tumor progression in diffuse large B-cell lymphoma

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 699-713 doi: 10.1007/s11684-022-0972-8

Abstract: achieved 40%–50% long-term complete response in relapsed or refractory diffuse

Keywords： anti-CD19 chimeric antigen receptor T     immunotherapy     diffuse large B cell lymphoma     tumor microenvironment    

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Suitability of common models to estimate hydrology and diffuse water pollution in North-eastern German

Muhammad WASEEM, Frauke KACHHOLZ, Jens TRÄNCKNER

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 4,   Pages 420-431 doi: 10.15302/J-FASE-2018243

Abstract:

Various process-based models are extensively being used to analyze and forecast catchment hydrology and water quality. However, it is always important to select the appropriate hydrological and water quality modeling tools to predict and analyze the watershed and also consider their strengths and weaknesses. Different factors such as data availability, hydrological, hydraulic, and water quality processes and their desired level of complexity are crucial for selecting a plausible modeling tool. This review is focused on suitable model selection with a focus on desired hydrological, hydraulic and water quality processes (nitrogen fate and transport in surface, subsurface and groundwater bodies) by keeping in view the typical lowland catchments with intensive agricultural land use, higher groundwater tables, and decreased retention times due to the provision of artificial drainage. In this study, four different physically based, partially and fully distributed integrated water modeling tools, SWAT (soil and water assessment tool), SWIM (soil and water integrated model), HSPF (hydrological simulation program– FORTRAN) and a combination of tools from DHI (MIKE SHE coupled with MIKE 11 and ECO Lab), have been reviewed particularly for the Tollense River catchment located in North-eastern Germany. DHI combined tools and SWAT were more suitable for simulating the desired hydrological processes, but in the case of river hydraulics and water quality, the DHI family of tools has an edge due to their integrated coupling between MIKE SHE, MIKE 11 and ECO Lab. In case of SWAT, it needs to be coupled with another tool to model the hydraulics in the Tollense River as SWAT does not include backwater effects and provision of control structures. However, both SWAT and DHI tools are more data demanding in comparison to SWIM and HSPF. For studying nitrogen fate and transport in unsaturated, saturated, and river zone, HSPF was a better model to simulate the desired nitrogen transformation and transport processes. However, for nitrogen dynamics and transformations in shallow streams, ECO Lab had an edge due its flexibility for inclusion of user-desired water quality parameters and processes. In the case of SWIM, most of the input data and governing equations are similar to SWAT but it does not include water bodies (ponds and lakes), wetlands and drainage systems. In this review, only the processes that were needed to simulate the Tollense River catchment were considered, however the resulted model selection criteria can be generalized to other lowland catchments in Australia, North-western Europe and North America with similar complexity.

Keywords： diffuse pollution     ECO Lab     HSPF     lowland catchment     MIKE 11     MIKE SHE     modeling tools     SWAT     SWIM     Tollense River    

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Phase I study of CBM.CD19 chimeric antigen receptor T cell in the treatment of refractory diffuse large

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 285-294 doi: 10.1007/s11684-021-0843-8

Abstract: second-generation anti-CD19 CAR bearing 4-1BB costimulatory molecule, for the treatment of patients with refractory diffuse

Keywords： CAR-T cell therapy     refractory diffuse large B-cell lymphoma     cytokine release syndrome     dose-limiting    

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Hydraulic Pressure Extremes Ratio & Extremes Ratio Efficiencies

Qi Maolin

Strategic Study of CAE 2001, Volume 3, Issue 4,   Pages 73-75

Abstract: applies basic formula to the calculation of a relationship between the hydraulic pressure extremes ratioof hydraulic system and the extremes ratio efficiencies.This relationship shows that the greater the hydraulic pressure extremes ratio is, the lower the extremesratio efficiencies are.The article holds that the hydraulic pressure extremes ratio can be designed and chosen.

Keywords： hydraulic pressure extremes ratio     extremes ratio efficiencies     hydraulic system    

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Treatment of severe diffuse cavernous hemangioma of the lower limb by combination of superficial femoral

Yin XIA, Dan SHANG, Qin LI, Xiaoqin RUN, Chenxi OUYANG, Yiqing LI, Bi JIN

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 240-244 doi: 10.1007/s11684-009-0031-8

Abstract: Severe diffuse cavernous hemangioma of the lower limb is rarely seen among young people and sometimesWe reported a case of diffuse cavernous hemangioma involving both skin and muscles of the left lower

Keywords： cavernous hemangioma     femoral artery     ligation     amputation    

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Controlling interstory drift ratio profiles via topology optimization strategies

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 2,   Pages 165-178 doi: 10.1007/s11709-022-0892-3

Abstract: proposed approach involves solving a min–max optimization problem to suppress the maximum interstory drift ratioThe proposed methodology can shape the interstory drift ratio profiles into inverted triangular or quadratic

Keywords： interstory drift ratio     aggregation function     bound formulation     min–max problem     topology optimization    

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Presence of multiple abnormal immunologic markers is an independent prognostic factor of diffuse large

Yiwen Cao, Zhenhua Liu, Wen Wu, Ying Qian, Qin Shi, Rong Shen, Binshen Ouyang, Pengpeng Xu, Shu Cheng, Jin Ye, Yiming Lu, Chaofu Wang, Chengde Yang, Li Wang, Weili Zhao

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 94-103 doi: 10.1007/s11684-019-0680-1

Abstract: to analyze the prognostic value of pretreatment immunologic markers in newly diagnosed patients with diffuse

Keywords： immunologic marker     diffuse large B-cell lymphoma     prognosis    

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A methodology of implementing target mixing ratio for asphalt mixture

Yucheng HUANG, Lun JI, Rui WEN, Ming ZHANG

Frontiers of Structural and Civil Engineering 2017, Volume 11, Issue 3,   Pages 308-314 doi: 10.1007/s11709-017-0405-y

Abstract: of hot mix asphalt adequately during the construction process, the significance of objective mixing ratioThe results show that the set of methods can not only implement the objective mixing ratio of hot mix

Keywords： asphalt mixture     target mixing ratio     mix design implementation     batching & mixing plant debugging    

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Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 11-14 doi: 10.1007/s11684-008-0003-4

Abstract: Using the plasma aldosterone concentration to plasma renin activity ratio (PAC/PRA ratio) as the screeninghypertensive patients, we studied the clinical characteristics and the diagnostic value of PAC/PRA ratioOne hundred and twenty-six suspected primary aldosteronism patients whose PAC/PRA ratio was > 25 ng/dLThe PAC/PRA ratio can be considered as a routine screening test in hypertensives, especially resistanthypertensive patients and a high PAC/PRA ratio is an invaluable index in primary aldosteronism diagnosis
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Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1522-y

Abstract:

• Simultaneous C & N removal in Methammox occurs at wide C:N ratio.

Keywords： Methanogens     Biological Nitrogen Removal (BNR)     Simultaneous     Methammox     C:N ratio    

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Experimental study of structural damage identification based on modal parameters and decay ratio of acceleration

Zhigen WU, Guohua LIU, Zihua ZHANG

Frontiers of Structural and Civil Engineering 2011, Volume 5, Issue 1,   Pages 112-120 doi: 10.1007/s11709-010-0069-3

Abstract: A novel damage assessment method based on the decay ratio of acceleration signals (DRAS) was proposed

Keywords： damage assessment     decay ratio of acceleration signals (DRAS)     wavelet transform (WT)     modal analysis     reinforced    

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The influence of the NCO/OH ratio and the 1,6-hexanediol/dimethylol propionic acid molar ratio on the

Jiao Feng, Qiuhao Lu, Weimin Tan, Kequan Chen, Pingkai Ouyang

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1,   Pages 80-89 doi: 10.1007/s11705-018-1763-2

Abstract: indicate that the degree of hydrogen bonding and the numbers of urea groups increase as the NCO/OH ratioand HDO/DMPA molar ratio increase.Furthermore, the phase separation increases and the thermal stability decreases as the NCO/OH ratio increasesor the HDO/DMPA molar ratio decreases.

Keywords： 1     5-pentamethylene diisocyanate     polyurethane     water based    

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Title Author Date Type Operation

Distribution and temporal variability of the solar resource at a site in south-east Norway

Muyiwa S. ADARAMOLA

Journal Article

Fully integrated approach: an alternative solution of coupling a GIS and diffuse pollution models

S. LIU,R.E. BRAZIER,A. L. HEATHWAITE,W. LIU

Journal Article

Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Journal Article

Immunosuppressive tumor microenvironment contributes to tumor progression in diffuse large B-cell lymphoma

Journal Article

Suitability of common models to estimate hydrology and diffuse water pollution in North-eastern German

Muhammad WASEEM, Frauke KACHHOLZ, Jens TRÄNCKNER

Journal Article

Phase I study of CBM.CD19 chimeric antigen receptor T cell in the treatment of refractory diffuse large

Journal Article

Hydraulic Pressure Extremes Ratio & Extremes Ratio Efficiencies

Qi Maolin

Journal Article

Treatment of severe diffuse cavernous hemangioma of the lower limb by combination of superficial femoral

Yin XIA, Dan SHANG, Qin LI, Xiaoqin RUN, Chenxi OUYANG, Yiqing LI, Bi JIN

Journal Article

Controlling interstory drift ratio profiles via topology optimization strategies

Journal Article

Presence of multiple abnormal immunologic markers is an independent prognostic factor of diffuse large

Yiwen Cao, Zhenhua Liu, Wen Wu, Ying Qian, Qin Shi, Rong Shen, Binshen Ouyang, Pengpeng Xu, Shu Cheng, Jin Ye, Yiming Lu, Chaofu Wang, Chengde Yang, Li Wang, Weili Zhao

Journal Article

A methodology of implementing target mixing ratio for asphalt mixture

Yucheng HUANG, Lun JI, Rui WEN, Ming ZHANG

Journal Article

Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Journal Article

Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:

Journal Article

Experimental study of structural damage identification based on modal parameters and decay ratio of acceleration

Zhigen WU, Guohua LIU, Zihua ZHANG

Journal Article

The influence of the NCO/OH ratio and the 1,6-hexanediol/dimethylol propionic acid molar ratio on the

Jiao Feng, Qiuhao Lu, Weimin Tan, Kequan Chen, Pingkai Ouyang

Journal Article